HIV PROTEASE INHIBITORS DISRUPT LIPID METABOLISM BY ACTIVATING ENDOPLASMIC RETICULUM STRESS AND INHIBITING AUTOPHAGY ACTIVITY IN ADIPOCYTES.

HIV protease inhibitors disrupt lipid metabolism by activating endoplasmic reticulum stress and inhibiting autophagy activity in adipocytes.

BackgroundHIV protease inhibitors (PI) are core components of Highly Active Antiretroviral Therapy (HAART), the most effective treatment for HIV infection currently available.However, HIV PIs have now been linked to lipodystrophy and dyslipidemia, which are major risk factors for cardiovascular disease and metabolic syndrome.Our previous studies ha

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Early-Season Crop Mapping on an Agricultural Area in Italy Using X-Band Dual-Polarization SAR Satellite Data and Convolutional Neural Networks

Early-season crop mapping provides decision-makers with timely information on crop types and conditions that are crucial for agricultural management.Current satellite-based mapping solutions mainly rely on optical imagery, albeit limited by weather conditions.Very few exploit long-time series of polarized synthetic aperture radar (SAR) imagery.To a

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